2017

• April 3 – Detroit at Sox* 6-3 L
• April 5 – Detroit at Sox
• April 6 – Detroit at Sox 11-2 W
• April 7 – Minnesota at Sox 3-1 L
• April 8 – Minnesota at Sox 6-2 W
• April 9 – Minnesota at Sox 4-1 L
• April 11 – Sox at Cleveland 2-1 L
  
• April 12 – Sox at Cleveland 2-1 W
• April 13 – Sox at Cleveland 10-4 W
  
• April 14 – Sox at Minnesota 2-1 W
  
• April 15 – Sox at Minnesota 6-0 L
  
• April 16 – Sox at Minnesota 4-1 L
  
• April 17 – Sox at Yankees 7-4 L
  
• April 18 – Sox at Yankees 4-1 W
  
• April 19 – Sox at Yankees 9-1 L
  
• April 21 – Cleveland at Sox 3-0 L
• April 22 – Cleveland at Sox 7-0 L
• April 23 – Cleveland at Sox 6-2 W
• April 24 – Kansas City at Sox 12-1 W
• April 25 – Kansas City at Sox 10-5 W
• April 26 – Kansas City at Sox 5-2 W
• April 28 – Sox at Detroit 7-3 W
  
• April 29 – Sox at Detroit 6-4 W
  
• April 30 – Sox at Detroit 7-3 L
  
• May 1 – Sox at Kansas City 6-1 L
  
• May 2 – Sox at Kansas City 6-0 W
  
• May 3 – Sox at Kansas City 6-1 L
  
• May 4 – Sox at Kansas City 8-3 W
  
• May 5 – Sox at Baltimore 4-2 L
  
• May 6- Sox at Baltimore 6-5 L
  
• May 7 – Sox at Baltimore 4-0 L
  
• May 9 – Minnesota at Sox 7-2 L
• May 10 – Minnesota at Sox PPD
• May 11 – Minnesota at Sox 7-6 L
• May 12 – San Diego at Sox 6-3 L
• May 13 – San Diego at Sox 5-4 W
• May 14 – San Diego at Sox 9-3 W
• May 15 – Sox at Anaheim 5-3 L
  
• May 16 – Sox at Anaheim 7-6 L
  
• May 17 – Sox at Anaheim 12-8 L
  
• May 18 – Sox at Seattle 5-4 L
  
• May 19 – Sox at Seattle 2-1 W
  
• May 20 – Sox at Seattle 16-1 W
  
• May 21 – Sox at Seattle 8-1 W
  
• May 22 – Sox at Arizona 5-1 L
  
• May 23 – Sox at Arizona 5-4 L
  
• May 24 – Sox at Arizona 8-6 L
  
• May 26 – Detroit at Sox 8-2 W
• May 27 – Detroit at Sox 3-0 W, 4-3 L
• May 28 – Detroit at Sox 7-3 W
• May 29 – Boston at Sox 5-4 W
• May 30 – Boston at Sox 13-7 L
• May 31 – Boston at Sox 4-1 L
• June 2 – Sox at Detroit 15-5 L
  
• June 3 – Sox at Detroit 10-1 L
  
• June 4 – Sox at Detroit 7-4 L
  
• June 6 – Sox at Tampa Bay 4-2 W
  
• June 7 – Sox at Tampa Bay 3-1 L
  
• June 8 – Sox at Tampa Bay 7-5 L
  
• June 9 – Sox at Cleveland 7-3 L
  
• June 10 – Sox at Cleveland 5-3 W
  
• June 11 – Sox at Cleveland 4-2 L
  
• June 12 – Baltimore at Sox 10-7 W
• June 13 – Baltimore at Sox 6-1 W
• June 14 – Baltimore at Sox 10-6 L
• June 15 – Baltimore at Sox 5-2 W
• June 16 – Sox at Toronto 11-4 W
  
• June 17 – Sox at Toronto 5-2 W
  
• June 18 – Sox at Toronto 7-3 L
  
• June 20 – Sox at Minnesota 9-7 L
  
• June 21 – Sox at Minnesota 4-2 L
  
• June 22 – Sox at Minnesota 9-0 W
  
• June 23 – Oakland at Sox 3-0 L
• June 24 – Oakland at Sox 10-2 L
• June 25 – Oakland at Sox 5-3 L
• June 26 – Yankees at Sox 6-5 L
• June 27 – Yankees at Sox 4-3 W
• June 28 – Yankees at Sox 12-3 L
• June 29 – Yankees at Sox 4-3 W
• June 30 – Texas at Sox 8-7 W
• July 1 – Texas at Sox 10-4 L
• July 2 – Texas at Sox 6-5 W
• July 3 – Sox at Oakland 7-2 W
  
• July 4 – Sox at Oakland 7-6 L
  
• July 5 – Sox at Oakland 7-4 L
  
• July 7 – Sox at Colorado 12-4 L
  
• July 8 – Sox at Colorado 5-4 W
  
• July 9 – Sox at Colorado 10-0 L
  
• July 11 – MLB All Star Game
• July 14 – Seattle at Sox 4-2 L
• July 15 – Seattle at Sox
• July 16 – Seattle at Sox
• July 18 – Los Angeles at Sox
• July 19 – Los Angeles at Sox
• July 21 – Sox at Kansas City
• July 22 – Sox at Kansas City
• July 23 – Sox at Kansas City
• July 24 – Sox at Cubs
• July 25 – Sox at Cubs
• July 26 – Cubs at Sox
• July 27 – Cubs at Sox
• July 28 – Cleveland at Sox
• July 29 – Cleveland at Sox
• July 30 – Cleveland at Sox
• July 31 – Toronto at Sox
• August 1 – Toronto at Sox
• August 2 – Toronto at Sox
• August 3 – Sox at Boston
• August 4 – Sox at Boston
• August 5 – Sox at Boston
• August 6 – Sox at Boston
• August 8 – Houston at Sox
• August 9 – Houston at Sox
• August 10 – Houston at Sox
• August 11 – Kansas City at Sox
• August 12 – Kansas City at Sox
• August 13 – Kansas City at Sox
• August 15 – Sox at Los Angeles
• August 16 – Sox at Los Angeles
• August 17 – Sox at Texas
• August 18 – Sox at Texas
• August 19 – Sox at Texas
• August 20 – Sox at Texas
• August 21 – Minnesota at Sox
• August 22 – Minnesota at Sox
• August 23 – Minnesota at Sox
• August 24 – Minnesota at Sox
• August 25 – Detroit at Sox
• August 26 – Detroit at Sox
• August 27 – Detroit at Sox
• August 29 – Sox at Minnesota
• August 30 – Sox at Minnesota
• August 31 – Sox at Minnesota
• September 1 – Tampa Bay at Sox
• September 2 – Tampa Bay at Sox
• September 3 – Tampa Bay at Sox
• September 4 – Cleveland at Sox
• September 5 – Cleveland at Sox
• September 6 – Cleveland at Sox
• September 7 – Cleveland at Sox
• September 8 – San Francisco at Sox
• September 9 – San Francisco at Sox
• September 10 – San Francisco at Sox
• September 11 – Sox at Kansas City
• September 12 – Sox at Kansas City
• September 13 – Sox at Kansas City
• September 14 – Sox at Detroit
• September 15 – Sox at Detroit
• September 16 – Sox at Detroit
• September 17 – Sox at Detroit
• September 19 – Sox at Houston
• September 20 – Sox at Houston
• September 21 – Sox at Houston
• September 22 – Kansas City at Sox
• September 23 – Kansas City at Sox
• September 24 – Kansas City at Sox
• September 25 – Anaheim at Sox
• September 26 – Anaheim at Sox
• September 27 – Anaheim at Sox
• September 28 – Anaheim at Sox
• September 29 – Sox at Cleveland
• September 30 – Sox at Cleveland
• October 1 – Sox at Cleveland